Table 3.

Additive total score and related rate of OS and PFS at 3 years

Additive total score	Patient status	No. of patients (%)	% (95% CI)		Cumulative incidence at 12 mo, %
			OS	PFS	Treatment discontinuation	Grade 3-4 nonhematologic AEs
0	Fit	340 (39)	84 (78-89)	48 (41-56)	16	22
1	Intermediate-fitness	269 (31)	76 (67-82)	41 (32-49)	21	26
≥2	Frail	260 (30)	57 (45-68)	33 (25-41)	31	34

In the univariate Cox model, the Harrell C index = 0.6608 and the AIC = 1766.077. In the multivariate Cox model, the Harrell C index = 0.7092 and the AIC = 1743.353.