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. 2014 Mar 1;52(4):2336–2343. doi: 10.1007/s13197-014-1275-0

Table 2.

Central composite design for independent variables and their response

Runs A
(Ethanol concentration (%))
B
(Time (h))
C
(Temperture (°C))
D
(Liquid–solid ratio (mL/g)
Yield
(mg/g)
1 1 0 0 1 13.950
2 0 1 0 −1 17.746
3 0 0 0 0 18.649
4 1 1 0 0 15.243
5 0 1 −1 0 15.488
6 −1 1 0 0 17.984
7 1 −1 0 0 14.842
8 0 0 −1 −1 15.583
9 1 0 0 −1 13.494
10 0 0 1 1 17.147
11 0 0 0 0 18.354
12 0 −1 0 1 16.689
13 0 0 0 0 19.180
14 −1 0 −1 0 17.899
15 −1 0 0 −1 15.466
16 −1 0 1 0 18.354
17 0 1 1 0 17.329
18 0 −1 0 −1 17.104
19 0 0 0 0 19.90
20 −1 0 0 1 20.396
21 0 −1 −1 0 15.618
22 0 −1 1 0 17.289
23 0 0 −1 1 16.727
24 −1 −1 0 0 15.688
25 1 0 1 0 14.892
26 0 0 0 0 16.733
27 0 0 1 −1 18.951
28 1 0 −1 0 14.962
29 0 1 0 1 16.542