Table 4. Multivariate-adjusted eGFR in T₁ and T₂+T₃ of serum (EPA+DHA):AA ratio in the Sasayama study, 2012–2013.

	Tertile of serum (EPA+DHA):AA		P valuea
	T1 (0.338–0.925)	T2+T3 (0.928–3.188)
Number of participants	184	365
Mean eGFRcre (ml/min/1.73 m2)
Sex- and age-adjusted	72.7 (70.8–74.7)	73.4 (72.0–74.8)	0.598
Multivariate-adjusted (Model 1)b	72.3 (70.3–74.3)	73.6 (72.3–75.0)	0.291
Multivariate-adjusted (Model 2)c	72.3 (70.3–74.2)	73.6 (72.3–75.0)	0.282
Mean eGFRcys (ml/min/1.73 m2)
Sex- and age-adjusted	86.9 (84.7–89.0)	90.7 (89.2–92.1)	0.006
Multivariate-adjusted (Model 1)b	86.9 (84.9–89.0)	90.6 (89.2–92.0)	0.005
Multivariate-adjusted (Model 2)c	86.9 (84.9–88.9)	90.6 (89.3–92.0)	0.004

AA, arachidonic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; GFR, glomerular filtration rate.

^aP value for ANCOVA.

^bMultivariate-adjusted (Model 1): eGFR adjusted for age, sex, BMI, hypertension, diabetes, HDL-C, LDL-C, medication for dyslipidemia, current smoking, and current drinking.

^cMultivariate-adjusted (Model 2): eGFR adjusted for variables in model 1 plus log-transformed high-sensitivity C-reactive protein.

Multivariate-adjusted (Model 2): eGFR adjusted for variables in model 1 plus log-transformed high-sensitivity C-reactive protein.