FIG 3.

Protective efficacy of cαStx2 given intramuscularly to B2F1-infected mice. Str-treated, B2F1-infected mice were given cαStx2 intramuscularly either 24 h before (A) or 24 h after (B) infection. The same control animals were used for the experiments whose results are shown in panels A and B; n = 15 for the control group and the 0.1 mg/kg group administered cαStx2 before infection; n = 10 for the 0.5 and 1.0 mg/kg doses given before or after infection; n = 5 for the 0.01 mg/kg dose given before or after infection. The antibody provided protection better than that seen with the control (no injection) for all doses except 0.001 mg/kg cαStx2 given after infection. P < 0.001 for the 0.1, 0.5, and 1.0 mg/kg doses given either before or after infection; P = 0.022 for the 0.1 mg/kg dose given before infection.