TABLE 1.
Group | Product | Dose or dilution (day[s] administered)a | No. of survivors/total no. | % survival | Time to death (days) |
||
---|---|---|---|---|---|---|---|
Avg | SD | Range | |||||
1 | Buffer | NAb | 0/16 | 0 | 4.6 | 1.4 | 3.1–8.7 |
2 | AdVAV | 7.5 × 107 vp (0) | 29/32 | 91 | 5.2 | 0.6 | 4.8–5.8 |
3 | AdVAV | 1.5 × 109 vp (0) | 31/32 | 97 | 4.1 | NA | NA |
4 | AdVAV | 3.5 × 1010 vp (0) | 32/32 | 100 | NA | NA | NA |
5 | AdVAV | 3.5 × 1010 vp (0, 28) | 31/32 | 97 | 6.1 | NA | NA |
6 | AVA | 1:16 (0, 28) | 31/32 | 97 | 3.0 | NA | NA |
7 | AVA | 1:64 (0, 28) | 25/32 | 78 | 4.5 | 0.8 | 3.8–6.1 |
The vaccine dose is shown as viral particles (vp) for AdVAV or as a dilution for the AVA vaccine.
NA, not applicable.