TABLE 3.
Circulating serum levels of PA following challenge
| Group | Product | Dose or dilution (day[s] administered) | Concn of circulating PA on SD74a (95% CI) |
|---|---|---|---|
| 1 | Buffer | NA | 33.3 (1.25–890) |
| 2 | AdVAV | 7.5 × 107 vp (0) | 0.0782 (0.0536–0.114) |
| 3 | AdVAV | 1.5 × 109 vp (0) | 0.0814 (0.0515–0.129) |
| 4 | AdVAV | 3.5 × 1010 vp (0) | 0.0650 (0.0650–0.0650) |
| 5 | AdVAV | 3.5 × 1010 vp (0, 28) | 0.0746 (0.0564–0.0986) |
| 6 | AVA | 1:16 (0, 28) | 0.0650 (0.0650–0.0650) |
| 7 | AVA | 1:64 (0, 28) | 0.113 (0.0600–0.212) |
a
Geometric mean concentrations are given. Sample concentrations below the assay LOD of 1.3 ng/ml were assigned a value of half LOD (0.065 ng/ml). SD74, study day 74.