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. 2015 Mar 26;2015:bav015. doi: 10.1093/database/bav015

Table 3.

Genes encoding the 15 promising drug targets

Rank Gene Symbol P-valuea
1 TP53 5.06 × 10−6
2 EGFR 1.37 × 10−4
3 UBE2I 1.37 × 10−4
4 CCND1 6.33 × 10−4
5 TOP1 6.33 × 10−4
6 MECP2 5.06 × 10−3
7 IMPDH2 6.74 × 10−3
8 NOS3 6.74 × 10−3
9 XRCC1 6.74 × 10−3
10 GNAS 0.0087
11 VEGFA 0.0139
12 PTGS2 0.0207
13 CFH 0.0296
14 MSH6 0.0437
15 GSTP1 0.0469

aP-value was calculated based on score distribution.