Table 1.
Participants |
||||
---|---|---|---|---|
all participants | 2008 | 2009 | 2010 | |
Number | 299 | 130 | 89 | 80 |
Male, n (%) | 280 (94) | 115 (88) | 85 (96) | 80 (100) |
Female, n (%) | 19 (6) | 15 (12) | 4 (4) | 0 |
Age at enrolment (years), median (range) | 23 (17–47) | 23 (17–46) | 22 (18–47) | 23 (17–45) |
Thai ethnicity, n (%) | 297 (99) | 130 (100) | 87 (98) | 80 (100) |
Exposure, n (%) | ||||
MSM | 264 (88) | 100 (77) | 84 (94) | 80 (100) |
MSM and intravenous drug users | 1 (0) | 1 (1) | 0 (0) | 0 (0) |
heterosexual | 34 (11) | 29 (22) | 5 (6) | 0 (0) |
HIV RNA (copies/mL), median (range)a | 37 020 (39–10 000 000) | 28 340 (376–948 200) | 40 660 (375–10 000 000) | 64 040 (39–2 459 000) |
CD4 count (cells/mm3), median (range)b | 348 (9–1007) | 357 (9–1007) | 350 (31–666) | 345 (89–842) |
CD4%, median (range)b | 18 (1–42) | 18 (1–42) | 18 (3–34) | 17 (7–35) |
Subtype (with sequences), n (%) | ||||
B | 25 (8) | 12 (9) | 7 (8) | 6 (8) |
CRF01_AE | 232 (78) | 102 (78) | 68 (76) | 62 (78) |
A | 10 (3) | 2 (2) | 5 (6) | 3 (4) |
AB | 9 (3) | 4 (3) | 2 (2) | 3 (4) |
BA | 3 (1) | 2 (2) | 0 (0) | 1 (1) |
BD | 2 (1) | 0 (0) | 2 (2) | 0 (0) |
recombinantc | 3 (1) | 2 (2) | 0 (0) | 1 (1) |
unsequenced | 15 (5) | 6 (5) | 5 (6) | 4 (5) |
aP value comparing 2008 and 2010: <0.01.
bCD4 count data were missing in 7, 43 and 14 patients in 2008, 2009 and 2010, respectively, and 1 additional patient in 2009 was missing the CD4%.
cNot defined further by the Rega subtyping tool. Manual examination of all three sequences suggested they are BA recombinants.