Figure 2.

Acetylation of multiple lysines in WT- and ALS-variant apo-SOD1 by aspirin. Electrospray ionization mass spectra of soluble (A) WT, (B) D90A, and (C) A4V apo-SOD1 after reaction with different concentrations of aspirin (in aqueous buffer). The mean number of acetylated lysines are denoted as Lys-Ac(∼N), and are listed per apo-SOD1 monomer. To see this figure in color, go online.