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. 2015 Mar 24;108(6):1555–1565. doi: 10.1016/j.bpj.2014.12.058

Figure 3.

Figure 3

Pattern selection achieved through a spatially localized signal. (A and B) Paths (arrows) 2a (A) and 2b (B) in the parameter space of Fig. 1, A and B. These paths involve transient temporal changes of a single parameter value (Fig. S9) acting in a cluster of cells. (Solid circles) Initial and final points of the paths; (open circles) intermediate vertex points. (C and D) Snapshots of the tissue state over time (t) when the system initially (t = 0) exhibits the H-pattern and the signal acts only in three cells (green cell borders), which change their control parameter values transiently according to paths 2a (C) and 2b (D). The remaining cells of the tissue have constant parameter values corresponding to those of parameter space point C. Parameter values are τ = 50 and tup = 11 and those in Fig. 1. To see this figure in color, go online.