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. 2015 Mar 5;96(3):440–447. doi: 10.1016/j.ajhg.2014.12.026

Figure 3.

Figure 3

Increased Keratinocyte Apoptosis in Lesional Skin

(A and B) TUNEL assay demonstrated increased apoptotic level of keratinocytes in lesional skin from individual 1 (B) compared to the control (A). The scale bars represent 50 μm.

(C and D) TEM of lesional skin from individual 1 showed expanded intercellular spaces (D, asterisks) compared to the control (C). The scale bars represent 5 μm.

(E) At higher magnification, chromatin condensation and margination (arrows) were apparent. The scale bar represents 2 μm.