Figure 3.

Predicted Mean Neandertal Allele Frequency at the End of the Population Bottlenecks in East Asian and European Populations for the Additive Case

(A) Population sizes were set to those inferred in Keinan et al.¹¹

(B) The ASN population size was assumed to be 5-fold smaller than that estimated in Keinan et al.¹¹ In all cases, constant-sized populations were simulated for 100 generations. The bottom plots show how Ns changes as a function of s.

In (A), both populations have a similar value of Ns across the range of s. Alleles with s > −0.0018 are nearly neutral (Ns > −1) in both populations. In (B), when s < −0.0018, alleles in the ASN population remain nearly neutral, whereas those in the EUR population are more strongly selected. Here, f = 2%.