Table 1.
Demographics and clinical features of primary biliary cirrhosis patients at hepatocellular carcinoma diagnosis n (%)
| Variable | Total | Men | Women | P value1 |
| (n = 52) | (n = 16) | (n = 36) | ||
| Age (yr) | 65.75 ± 10.09 | 69.75 ± 8.09 | 63.97 ± 10.47 | 0.093 |
| Han nationality | 47 (90.38) | 14 (87.50) | 33 (91.67) | 0.638 |
| Body mass index ≥ 25 (kg/m2) | 16 (30.77) | 4 (25.00) | 12 (33.33) | 0.548 |
| History of blood transfusion | 6 (11.54) | 3 (18.75) | 3 (8.33) | 0.043 |
| Past HBV infection | 29 (55.77) | 10 (62.50) | 19 (52.78) | 0.519 |
| Alcohol intake | 8 (15.38) | 5 (31.25) | 3 (8.33) | 0.035 |
| Smoking | 8 (15.38) | 5 (31.25) | 3 (8.33) | 0.010 |
| Type 2 diabetes mellitus | 8 (15.38) | 0 | 8 (22.22) | 0.040 |
| Hypertension | 12 (23.08) | 5 (31.25) | 7 (19.44) | 0.165 |
| Family history of malignancy | 6 (11.54) | 4 (25.00) | 2 (5.56) | 0.012 |
| Liver cirrhosis | 52 (100.00) | 16 (100.00) | 36 (100.00) | 1.000 |
| Tumor size | ||||
| ≥ 3 cm | 35 (67.31) | 11 (68.75) | 24 (66.67) | 0.882 |
| < 3 cm | 17 (32.69) | 5 (31.25) | 12 (33.33) | 0.882 |
| Tumor number | ||||
| Single | 29 (55.77) | 9 (56.25) | 20 (55.56) | 0.963 |
| Multiple | 23 (44.23) | 7 (43.75) | 16 (44.44) | 0.963 |
| Pruritus | 4 (7.70) | 3 (18.75) | 1 (2.78) | 0.046 |
| Fatigue | 37 (71.15) | 13 (81.25) | 24 (66.67) | 0.284 |
| Anorexia | 20 (38.46) | 5 (31.25) | 15 (41.67) | 0.476 |
| Discomfort in hepatic region | 11 (21.15) | 4 (25.00) | 7 (19.44) | 0.651 |
| Jaundice | 30 (57.69) | 11 (68.75) | 19 (52.78) | 0.282 |
| Ascites | 41 (78.85) | 12 (75.00) | 29 (80.56) | 0.651 |
1
Men compared with women. HBV: Hepatitis B virus; NA: Not applicable.