Figure 2.

Predicted open fraction ƒ_O(t) for a 1.5 s pulse of agonist over a wide range of concentrations (expressed relative to K_d,R = 167 μM) in equal multiplicative increments of 10^1/3 = 2.154. (a) c_ag/K_d,R = 0.01 (black line), 0.02154 (black dashed line), 0.04642 (black dotted line), 0.1 (black dot-dashed line), 0.2154 (blue line), 0.4642 (blue dashed line), 1 (blue dotted line), 2.154 (blue dot-dashed line), and 4.642 (red long dashed line). (b) c_ag/K_d,R = 4.642 (red long dashed line), 10 (black line), 21.54 (black dashed line), 46.42 (black dotted line), 100 (black dot-dashed line), 215.4 (blue line), 464.2 (blue dashed line), and 1000 (blue dotted line). To see this figure in color, go online.