Figure 3.

Predicted open fraction ƒ_O(t) for a 1.5 s pulse of coapplied agonist and isoflurane. (a) c_ag = 0.1K_d,R = 16.7 μM; c_an = 0 mM (black line), 0.15 mM (black dashed line), 0.3 mM (black dotted line), 0.5 mM (black dot-dashed line), 0.75 mM (blue line), 1.0 mM (blue dashed line), 1.25 mM (blue dotted line), 1.6 mM (blue dot-dashed line), 2.2 mM (red line), 3 mM (red dashed line), and 5 mM (red dotted line). (b) c_ag = 6K_d,R = 1.0 mM; c_an = 0 mM (black line), 0.2 mM (black dashed line), 0.7 mM (black dotted line), 1.6 mM (black dot-dashed line), 3 mM (blue line), 6 mM (blue dashed line), and 15 mM (blue dotted line). To see this figure in color, go online.