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T1rho (T1ρ) contrast from medial temporal lobe overlaid on anatomic fluid attenuated T1ρ weighted images of control (A), medial cognitive impairment (MCI, B), and Alzheimer's disease (AD, C) patients. A progressive increase in T1ρ contrast in medial temporal lobe (MTL) region was observed from control to MCI to AD. No T1ρ contrast from CSF was depicted.
