Estimates of Rind and Rpop as a Function of B-Value Cutoffs
(A) Amount of the genome in each B-value category. Note that each category is a subset of the category to its left (i.e., the category B ≥ 0 contains the entire genome).
(B and C) Rind (B) and Rpop (C) calculated over genomic regions with progressively higher B-value thresholds (i.e., less functional constraint; see color bar). Violin plots show bootstrap resamples, and red dotted lines denote the 95% confidence intervals (CIs).