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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Feb 19;35(4):779–782. doi: 10.1161/ATVBAHA.114.304525

Figure 1.

Figure 1

Loss of the endothelial glucocorticoid receptor accelerates atherosclerosis in Apo E −/− mice (A) Weight is significantly increased in both groups following 12 weeks of HFD feeding. (B) No significant difference in triglycerides before or after HFD. (C) Both groups show a statistically significant increase in cholesterol after HFD as expected. (D) No difference in corticosterone levels before or after HFD. (E) Representative examples of aortic Oil Red O staining with (F) quantification of aortic lesions. (G) Representative staining of brachiocephalic arteries with hematoxylin and eosin, Trichrome and Oil Red O staining with (H) quantification of lesion size. Data are mean ± SEM. n=5-8 mice/group. *p<0.05.