Fig. 4.

Functional characterization by behavioral domains and paradigm classes. A) Functional characterization by behavioral domains and paradigm classes of MOG-striatal atrophy seeds in premanifest HD (blue). B) Functional characterization by behavioral domains and paradigm classes of IFJ-striatal (green) and M1-striatal (red) atrophy seeds in manifest HD. Bar plots show significant associations (at p < 0.01, uncorrected) of behavioral domains and paradigm classes from the BrainMap meta-data given observed brain activity (and vice versa); the x-axis indicates relative probability values.