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. 2015 Jan-Feb;47(1):4–10. doi: 10.4103/0253-7613.150305

Figure 4.

Figure 4

Regulation of serotonin synthesis by brain leptin levels. Excessive brain leptin levels directly inhibit tryptophan hydroxylase-2 thereby decreasing the circulating neuronal levels of serotonin (5-hydroxytryptamine)[41]