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Estimated impact of demographic changes on VZV epidemiology (1900–2009). (a) Estimated age-specific VZV seroprevalence at different years. (b) Estimated mean age (and 95% CI, shaded areas) at varicella over time. (c) Estimated age-specific HZ incidence at different years. The inset shows the total HZ incidence over time and disaggregated by age group. (d) Estimated mean age (and 95% CI, shaded areas) at HZ over time.
