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. 2015 Mar 27;9:78. doi: 10.3389/fnbeh.2015.00078

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Copyright © 2015 Manto, Honnorat, Hampe, Guerra-Narbona, López-Ramos, Delgado-García, Saitow, Suzuki, Yanagawa, Mizusawa and Mitoma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of GAD65Ab on behavior of rats as assessed in open field test and elevated beam test. (A) Effects of bilateral administration of GAD65Ab in the interpositus nucleus on exploration behavior in rats (open field test). Four groups of five rats were assessed. The number of squares crossed was measured over a period of 3 min (five trials per rat). Box plots showing median values, p25 and p75 with outliers. **P < 0.001, *P < 0.05. (B) Displacement times (expressed in seconds) during the horizontal beam test. Four groups of three rats were assessed. Median with mean values (dotted lines) are shown, as well as p25/p75 and outliers. **P < 0.001, *P < 0.05.