TABLE 1.
Fertilization success of Parp11−/− sires achieved by in vivo mating with wild-type females compared to wild type sires (Fig. 1B). Embryo development assessment 36 h after natural mating revealed that despite the presence of vaginal plugs, natural fertilization rates were low if the male was Parp11−/−, consistent with low numbers of offspring produced by these males (Fig. 2A).