. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Arthritis Rheumatol. 2014 Dec;66(12):3476–3485. doi: 10.1002/art.38865

Table 2.

Circulating folate concentrations in JIA patients receiving or not receiving MTX therapy. Statistical comparisons were made by Wilcoxon's rank sum analysis.

		(-) MTX (Median [IQR])	(+) MTX (Median [IQR])	P-value
Total Folate (nmol/L)	Blood	450 [300, 534]	297 [218, 371]	< 0.0001
	Plasma	43 [27, 63]	29 [23, 41]	< 0.0001
	RBC	1161 [707, 1367]	728 [539, 926]	< 0.0001
CH=THF (nmol/L)	Blood	24 [15, 37]	21 [11, 33]	0.09
	Plasma	0.3 [0.3, 0.4]	2.0 [0.6, 2.5]	< 0.0001
	RBC	67 [36, 102]	51 [27, 84]	0.03
5mTHF (nmol/L)	Blood	404 [274, 495]	265 [187, 336]	< 0.0001
	Plasma	43 [26, 63]	27 [21, 40]	< 0.0001
	RBC	1033 [646, 1252]	643 [454, 829]	< 0.0001