TABLE 2.
Number of Genes Missing at 5 years as Determined by CGH
| EH Group* | H Group | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Monkey | EH1 | EH3 | EH4 | EH5 | H1 | H2 | H4 | H5 | H6 | |||||||||
| Biopsy ID (isolate designation)# | 4641(3) | 4694(2) | 4689(5) | 4690(1) | 4633(1) | 4633(2) | 4637(3) | 4637(5) | 4661(3) | 4662(1) | 4723(1) | 4723(2) | 4726(1) | 4726(2) | 4721(1) | 4722(3) | 4667(2) | 4668(1) |
| Dysplasia∞ | − | − | + | + | + | + | + | + | − | − | − | − | − | − | − | − | − | − |
| no. of missing genes | 16 | 15 | 0 | 9 | 0 | 2 | 1 | 20 | 26 | 24 | 1 | 0 | 1 | 5 | 3 | 2 | 23 | 22 |
*
Only 4 animals were included in this group; one animal died before CGH studies were initiated.
#
Two isolates per animal were analyzed by microarray
∞
Previously published data from this study showed that disease only develops in this model when H. pylori and the oral carcinogen ENNG are administered together (Liu et al., 2009).