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. 2015 Mar 20;8:18. doi: 10.1186/s13039-015-0120-0

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© Iossa et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Pedigree of the affected Italian family. Squares and circles symbolize males and females, respectively. Unblackened and blackened symbols denote unaffected and affected individuals, respectively. Circles with a dot inside denote carrier females. Diagonal lines denote deceased individuals. The arrow denotes the proband.