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. 2015 Mar 27;10(3):e0120261. doi: 10.1371/journal.pone.0120261

Fig 6. MDDC TLR-2 and DC-SIGN are required for appropriate cytokine responses to Lb. rhamnosus JB-1.

Fig 6

(A) Lb. rhamnosus JB-1 or Lb. murinus-stimulated MDDCs were pre-incubated with blocking antibodies for TLR-2 (n = 8 donors), DC-SIGN (n = 8 donors) or antibody isotype controls for 30 minutes prior to stimulation and cytokine secretion was analyzed after 24 hours. Results are expressed as the mean pg/ml +/− standard error. (B) TLR-2 activation was confirmed using HEK-293 cells which express TLR-2. *p<0.05