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Model parameters that matched experimental data
| Experimental group | τrefill (ms) | kopen (ms−1) |
|---|---|---|
| CTRL | 6.55 | 42 |
| ISO | 4.9 | 60 |
| Forskolin | 4.6 | 30 |
| H89 | 8.8 | 35 |
| S2808A | 5.5 | 42 |
| S2808A + ISO | 4.9 | 42 |
| ISO + KN92 | 4.5 | 90 |
| ISO + KN93 | 5.3 | 42 |
| ISO + H89 | 5.7 | 40 |
τrefill, time constant of refilling; kopen, maximum opening rate of the RyRs.
