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Simualtaneous activation of TRPV4 and inhibition of SK channels results in no change of action potential. (A) Raw ACf at 300 mOsm and with the addition of both GSK1016790A (100 nM) and UCL-1684 (30 nM). (B) Representative histogram showing that GSK1016790A and UCL-1684 together have no effect on ACf. (C) Mean ACf from experiments similar to those illustrated in (B) and (C) is not significantly changed with the addition of GSK1016790A and UCL-1684 (n = 7).
