Table 2.

Radiolabeling efficiency (%) of bifunctional chelates with ¹⁷⁷Lu (pH 5.5, RT)^#

Time (min)	Radiolabeling efficiency (%)
	3p-C-DE4TA* (1)	3p-C-NE3TA (2)	3p-C-NOTA (3)	3p-C-DEPA (4)	3p-C-NETA+ (5)	C-DOTA+
1	85.2 ± 0.7	6.7 ± 0.1	17.5 ± 0.5	93.9 ± 1.3	100.0 ± 0.0	94.5 ± 3.9
10	99.8 ± 0.3	36.6 ± 0.4	81.3 ± 0.2	98.7 ± 0.2	100.0 ± 0.0	99.5 ± 0.5
20	99.8 ± 0.1	63.2 ± 0.8	95.0 ± 0.2	99.2 ± 0.3	100.0 ± 0.0	99.9 ± 0.1
30	99.9 ± 0.1	78.1 ± 1.1	99.1 ± 0.4	99.4 ± 0.1	100.0 ± 0.0	99.9 ± 0.1
60	100.0 ± 0.1	95.0 ± 0.1	100 ± 0.1	99.3 ± 0.2	100.0 ± 0.0	100.0 ± 0.0

^#Radiolabeling efficiency (mean ± standard deviation%) was measured in triplicate using ITLC.

^*Radiolabeling efficiency was determined at pH 7 using ITLC.

⁺The data cited for comparison.¹⁶