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. Author manuscript; available in PMC: 2015 Sep 12.
Published in final edited form as: Nature. 2015 Feb 25;519(7542):187–192. doi: 10.1038/nature14259

Extended data Figure 3. dNotum requires Dally to inhibit Wingless signaling.

Extended data Figure 3

a, Wingless and Senseless expression in a dally−/− wing imaginal disc expressing NRT-wingless and notum under the control of dpp-Gal4. Some senseless expression remains, indicating that, in the absence of Dally, dNotum is a poor inhibitor of NRTWingless-induced (as well as endogenous) signalling. b-d, Anterior margin of wings from control, spalt (sal)-Gal4 UAS-notum-V5, and sal-Gal4 UAS-notum-V5 dally−/− animals. Removal of dally rescues the loss of margin bristles caused by dNotum overexpression.