Table 1.
Events | Time | Ref. | |
---|---|---|---|
Establishment of iPS cells | mice | 2006 | [15] |
human | 2007 | [21] | |
rhesus | 2008 | [25] | |
Pig, Rat | 2009 | [26, 27] | |
Canine; rabbit | 2010 | [28, 29] | |
Sheep; bovine | 2011 | [30, 31] | |
Cell origin for iPSCs production | fibroblast ; | 2006; | [32] |
skin; pancreatic beta cells; liver, stomach, beta cells, neural progenitor cells; keratinocytes | 2008 | [33–38] | |
Adipose stem cells; blood; Hemotopiotic cell; Melanocytes; Cord blood cells; | 2009 | [39–43] | |
dental tissues; circulating T cells; | 2010 | [44, 45] | |
endothelial cells; renal tubular cells; | 2011 | [46, 47] | |
Reprogramming strategies | Retroviral; | 2006; | [15] |
ectopic expression; | 2007; | [20] | |
ectopic expression; lentiviruses; onintegrating adenoviruses; Plamid; not integrate; free of exogenous genes.; | 2008; | [33, 34, 37, 48–51] | |
polycistronic; reprogramming proteins. | 2009; | [52–56] | |
piggyBac (PB) transposition; nonintegrating episomal vectors; recombinant proteins; | |||
'minicircle’ DNA | 2010; | [57] | |
miRNA; | 2011; | [58] |