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. 2013 Nov 8;1(1):6. doi: 10.1186/2050-490X-1-6

Table 1.

Development of cell reprograming

Events Time Ref.
Establishment of iPS cells mice 2006 [15]
human 2007 [21]
rhesus 2008 [25]
Pig, Rat 2009 [26, 27]
Canine; rabbit 2010 [28, 29]
Sheep; bovine 2011 [30, 31]
Cell origin for iPSCs production fibroblast ; 2006; [32]
skin; pancreatic beta cells; liver, stomach, beta cells, neural progenitor cells; keratinocytes 2008 [3338]
Adipose stem cells; blood; Hemotopiotic cell; Melanocytes; Cord blood cells; 2009 [3943]
dental tissues; circulating T cells; 2010 [44, 45]
endothelial cells; renal tubular cells; 2011 [46, 47]
Reprogramming strategies Retroviral; 2006; [15]
ectopic expression; 2007; [20]
ectopic expression; lentiviruses; onintegrating adenoviruses; Plamid; not integrate; free of exogenous genes.; 2008; [33, 34, 37, 4851]
polycistronic; reprogramming proteins. 2009; [5256]
piggyBac (PB) transposition; nonintegrating episomal vectors; recombinant proteins;
'minicircle’ DNA 2010; [57]
miRNA; 2011; [58]