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. 2015 Mar 27;10(3):e0122258. doi: 10.1371/journal.pone.0122258

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Fig 1 — DT3 (75 mg/kg) or vehicle was administered as a single subcutaneous injection to mice 24 h before total-body gamma-radiation (TBI) at a dose rate of 0.6 Gy/min. Thirty-day survival was monitored after different doses of gamma-radiation. Survival data were used to evaluate the DT3 dose reduction factor (DRF, N = 20 mice/group). The DRF of DT3 was determined to be 1.28 (p<0.01).