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. 2015 Jan 17;18(5):pyu028. doi: 10.1093/ijnp/pyu028

Figure 8.

Figure 8.

P7 ethanol treatment impairs and SR pretreatment rescues impaired spatial memory performance as measured by the Y maze. Discrimination ratio (preference for the novel arm over the familiar or other arm: Novel/Novel + Other) for arm entries (a and c) and dwell time (b and d) of S+V- and E+V-treated mice with or without SR in the Y maze at 1h and 24h after the first encounter with the partially-opened maze. The dashed line indicates chance performance (0.5). (e) The percentage of animals selecting the novel arm as the first choice is shown for S+V- and E+V-treated mice with or without SR at 1h and 24h after the first encounter with the partially-opened maze. Each point is the mean ± SEM (n = 8 mice/group). Two-way ANOVA with Bonferroni’s post hoc test: ***p < 0.001 vs. S + V; #p < 0.05 vs. E + V. Discrimination ratio (preference for the novel arm over the familiar or other arm: Novel/Novel + Other) for arm entries (f and h) and dwell time (g and i) of S+CB1RWT, E+CB1RWT, S+CB1RKO, and E+CB1RKO mice in the Y maze at 1h and 24h after the first encounter with the partially-opened maze. The dashed line indicates chance performance (0.5). (j) The percentage of animals selecting the novel arm as the first choice is shown for S+CB1RWT, E+CB1RWT, S+CB1RKO, and E+CB1RKO mice at 1h and 24h after the first encounter with the partially-opened maze. Each point is the mean ± SEM (n = 8 mice/group). Two-way ANOVA with Bonferroni’s post hoc test: ***p < 0.001 vs. S + V; #p ≤ 0.01 vs. E ± V; $ p ≤ 0.01 vs. S ± CB1RWT; @ p ≤ 0.01 vs. S ± CB1RWT.