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. 2015 Jan 24;18(5):pyu041. doi: 10.1093/ijnp/pyu041

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© The Author 2015. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Effects of chronic MK-801 (1mg/kg), clozapine (CLZ; 1mg/kg), and CBD (60mg/kg) treatment on PV protein expression in mouse mPFCs (n = 7/group). (A) MK-801 induced a decrease in the number of PV-positive cells in the mPFC. CBD and clozapine attenuated PV decrease in the mPFC. The data are presented as the mean ± SEM. *p < 0.05 vs. VEH + SAL group, #p < 0.05 vs. VEH + MK-801 group; two-way ANOVA followed by S-K-N test. (B) Photomicrographs of PV-like immunoreactivity in the mPFC (10X; Bar = 200 μm). CC: corpus callosum; mPFC: medial prefrontal cortex.