Table IV.
Characteristics of patients with and without CDKN2A and/or TP53 alterations
|
CDKN2A Deleted N=12 |
CDKN2A Normal N = 95 |
P-value |
TP53 Mutation N=8 |
TP53 Normal N=85 |
P-value | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Demographics | N | % | N | % | N | % | N | % | ||
| Age | 0.22 | 0.067 | ||||||||
| <=9 | 3 | 25% | 33 | 35% | 0 | 0% | 31 | 36% | ||
| 10-17 | 7 | 58% | 58 | 61% | 7 | 88% | 50 | 59% | ||
| 18<= | 2 | 17% | 4 | 4% | 1 | 13% | 4 | 5% | ||
| Sex | 0.76 | 0.72 | ||||||||
| Male | 6 | 50% | 53 | 56% | 4 | 50% | 50 | 59% | ||
| Female | 6 | 50% | 42 | 44% | 4 | 50% | 35 | 41% | ||
| Race | 0.75 | 0.013 | ||||||||
| Caucasian | 11 | 92% | 85 | 89% | 6 | 75% | 81 | 95% | ||
| African American | 0 | 0% | 2 | 2% | 1 | 13% | 0 | 0% | ||
| Asian | 0 | 0% | 1 | 1% | 1 | 13% | 0 | 0% | ||
| Other | 0 | 0% | 2 | 2% | 0 | 0% | 2 | 2% | ||
| Missing | 1 | 8% | 5 | 5% | 0 | 0% | 2 | 2% | ||
| Primary Tumor Site | 0.2 | 0.4 | ||||||||
| Appendicular | 4 | 33% | 38 | 40% | 2 | 25% | 31 | 36% | ||
| Thoracic | 0 | 0% | 15 | 16% | 1 | 13% | 13 | 15% | ||
| Pelvic | 4 | 33% | 15 | 16% | 2 | 25% | 1 | 1% | ||
| Other Axial | 2 | 17% | 6 | 6% | 0 | 0% | 9 | 11% | ||
| Extraosseous | 2 | 17% | 21 | 22% | 3 | 38% | 15 | 18% | ||