Fig. 5. The effect of VLN-NP in rat alkali burn-induced corneal NV model.
VLN-NP or LN-NP was administered topically onto the cornea 1 hr after alkali burn, and photographs were taken on day 7 following the administration. A: Representative photographs of rat corneas with indicated treatments. Arrows indicate corneal NV areas. B, C: Quantification of corneal NV by NV clock hour (B) and area (C) in each group. *p<0.05, **p<0.01, n=6. D: Representative rat cornea sections with H&E staining and immunostaining of an anti-CD31 antibody (green), and the nuclei counterstained with DAPI (blue). Magnification ×100. Arrows indicate NV areas in the cornea. Epi: epithelium; S: stroma; Endo: endothelium.
