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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Jan 22;35(4):911–917. doi: 10.1161/ATVBAHA.114.305150

Figure 1. TAA progression in mice with severe MFS.

Figure 1

(A) Quantified diameters of the aortic root (AoR) and proximal ascending aorta (AsA), and (B) combined scores of wall thickness and elastic lamella integrity (MD) in WT (black) Fbn1mgR/mgR (grey) mice of the indicated ages (n≥ 5 per time-point and genotype); asterisks indicate statistically significant differences between individual sets of WT and MFS samples (p<0.05).