Table 1. Effects of EPI against juvenile S. mansoni BH strain (treated 21 days post infection).

Sample	Dose	Mean worm burden ± SEM (liver and porto-mesenteric)				Reduction in total worm burden
		Male	Female	Couples	Total Worms
Control	0 (PBS only)	10.2±2.8	3.9±0.6	9.6±1.8	32.9±3.7	-
EPI	40 mg/kg	2.2±0.5*	2.4±0.6	5.9±0.7	16.4±1.7**	50.2%
EPI	300 mg/kg	6.8±1.4	0.9±0.3***	5.0±1.0*	17.6±1.4**	46.3%

Values are presented as mean ± SEM. Number of animals/group = 8.

Asterisks indicate that difference compared to the control was significant with ***P<0.001, **P<0.01 and *P<0.05.