Table 1. Main results of eQTL mapping under different false discovery (FDR) rates.
| Panel A: Without adjustment for RNA PCs, all subjects | ||||
|---|---|---|---|---|
| Pairs | Probes | Genes | SNPs | |
| FDR<0.01 | ||||
| local | 8117 | 921 | 841 | 7177 |
| distal | 1305 | 262 | 249 | 991 |
| FDR<0.05 | ||||
| local | 13857 | 1750 | 1596 | 11922 |
| distal | 2075 | 507 | 484 | 1524 |
| FDR<0.1 | ||||
| local | 18952 | 2649 | 2392 | 16087 |
| distnat | 2885 | 814 | 772 | 2017 |
| Panel B: Without adjustment for RNA PCs, controls | ||||
| Pairs | Probes | Genes | SNPs | |
| FDR<0.01 | ||||
| local | 1544 | 277 | 257 | 1421 |
| distal | 679 | 151 | 140 | 443 |
| FDR<0.05 | ||||
| local | 2763 | 508 | 478 | 2551 |
| distal | 1465 | 327 | 312 | 937 |
| FDR<0.1 | ||||
| local | 3911 | 797 | 753 | 3574 |
| distal | 2455 | 610 | 584 | 1514 |
| Panel C: Without adjustment for RNA PCs, cases | ||||
| Pairs | Probes | Genes | SNPs | |
| FDR<0.01 | ||||
| local | 1405 | 268 | 248 | 1281 |
| distal | 557 | 141 | 136 | 394 |
| FDR<0.05 | ||||
| local | 2628 | 507 | 475 | 2372 |
| distal | 1170 | 310 | 297 | 825 |
| FDR<0.1 | ||||
| local | 3837 | 819 | 761 | 3461 |
| distal | 1983 | 597 | 571 | 1353 |
| Panel D: With adjustment for RNA PCs, all subjects | ||||
| Pairs | Probes | Genes | SNPs | |
| FDR<0.01 | ||||
| local | 22323 | 2242 | 2008 | 18746 |
| distal | 1391 | 321 | 306 | 1051 |
| FDR<0.05 | ||||
| local | 36720 | 3808 | 3391 | 30386 |
| distal | 1851 | 461 | 446 | 1461 |
| FDR<0.1 | ||||
| local | 50270 | 5461 | 4799 | 40997 |
| distal | 2272 | 650 | 627 | 1853 |