Table 1. Comparison of serine peptidase RNAi screen with RIT-seq phenotypes.
| Family | Gene ID | Gene name | RIT-seq phenotype † | RNAi cell line phenotype |
|---|---|---|---|---|
| S8 Subtilisin | Tb927.3.4230 | subtilisin-like serine peptidase | Normal in all | Normal |
| Tb927.11.3780* | subtilisin-like serine peptidase | Abnormal in BSF 6d and PCF | Normal | |
| S9 Prolyloligopeptidase | Tb927.11.12850 | oligopeptidase B | Normal in all | Normal |
| Tb927.10.8020 | prolyl oligopeptidase, putative | Normal in all | Normal | |
| Tb927.5.4300 | prolyl oligopeptidase-like | Normal in all | Normal | |
| Tb927.10.6940 * | dipeptidyl peptidase | As for Tb927.10.6970 | Normal | |
| Tb927.10.6970 * | dipeptidyl peptidase | Normal in all | Normal | |
| Tb927.7.4940 * | oligopeptidase B-like | Abnormal in BSF 3d and 6d | Normal | |
| Tb11.v5.0175 * | oligopeptidase B-like | As for Tb927.7.4940 | Normal | |
| Tb927.9.10970 | BEM46-like | Normal in all | Normal | |
| Tb927.1.4780 | S9D serine peptidase | Abnormal in diff BSF | Normal | |
| Tb927.8.5760 | hypothetical protein | Abnormal in BSF 6d | Normal | |
| Tb927.6.1810 | hypothetical protein | Normal in all | Normal | |
| S10 Carboxypeptidase | Tb927.10.1030 | serine carboxypeptidase III precursor | Normal in all | Normal |
| Tb927.10.1040 | serine carboxypeptidase III precursor | As for Tb927.10.1030 | Normal | |
| Tb927.10.1050 | serine carboxypeptidase III precursor | As for Tb927.10.1030 | Normal | |
| S26 Signal peptidase | Tb927.10.4590 | mitochondrial inner membrane signal peptidase | Normal in all | Normal |
| Tb927.5.3220 | signal peptidase type I | Normal in all | Abnormal | |
| S54 Rhomboid | Tb927.2.2500 | hypothetical protein | Normal in all | Normal |
| S59 Nucleoporin | Tb927.11.980 | nucleoporin | Normal in all | Normal |
* Identical coding sequences
† 3d, 6d denote 3 and 6 days after induction of RNAi