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. 2015 Mar 27;10(3):e0121754. doi: 10.1371/journal.pone.0121754

Table 1. Clinical and laboratory information study participants with and without HBV and HCV, with different degrees of disease.

Variables HBV chronic hepatitis HCV chronic hepatitis Non-viral chronic hepatitis Normal control
Study subjects (n) 6 28 9 8
Gender (F/M) 4/2 16/12 5/4 5/3
ALT (UI/L) Mean ± SD 35.8 ± 60.8 89 ± 97.1 97 ± 76.21 27 ± 8.11
Median 30.5 56 96 27
GGT (UI/L) Mean ± SD 30 ± 14.7 78 ± 98.8 170 ± 141.77 29 ± 10.74
Median 20.5 55 155 29
Fibrosis Stage a
F0 (%) 1 (16.7) 2 (7.1) 1 (16.7) 8 (100.0)
F1 (%) 4 (66.6) 13 (46.5) 2 (33.3) -
F2 (%) - 7 (25.0) - -
F3 (%) - 3 (10.7) 1 (16.7) -
F4 (%) 1 (16.7) 3(10.7) 2 (33.3) -
Inflammation Stage b
A0 (%) 1 (16.7) 4 (14.3) 1 (16.7) 8 (100.0)
A1 (%) 4 (66.6) 13 (46.4) 4 (66.6) -
A2 (%) 1 (16.7) 11 (39.3) 1 (16.7) -

ALT: alanine aminotransferase; GGT: gamma-glutamyl transferase;

aFibrosis Stages—F0: no fibrosis; F1: portal without septa; F2: portal with some septa; F3: many septa without cirrhosis; F4: cirrhosis;

bInflammation Stages—A0: absent; A1: mild; A2: moderate.