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The wild type and the main common mutant alleles. TPMT*1 is the most common allele (wild type), while TPMT*3A is the most common variant allele in Caucasians and TPMT*3C is the most common variant allele in East Asians. Open rectangles represent open reading frames (ORF) while the blue rectangles represent 5′- and 3′-untranslated regions (UTR). Adapted from (10).
