Table 2.
Probability parameters (baseline value, low value and high value) used in decision tree model
| Variable | Baseline value | Low value | High value |
|---|---|---|---|
| Treatment with beclomethasone dipropionate nasal spray | |||
| Improvement of symptoms | 44.0 | 40.0 | 48.0 |
| Improvement of nasal symptoms | 50.0 | 45.0 | 50.0 |
| Improvement of ocular symptoms | 25.0 | 23.0 | 28.0 |
| Side effects | 77.0 | 69.0 | 85.0 |
| Epistaxis | 28.0 | 25.0 | 31.0 |
| Treatment with mometasone furoate nasal spray | |||
| Improvement of symptoms | 77.0 | 69.0 | 85.0 |
| Improvement of nasal symptoms | 43.0 | 39.0 | 47.0 |
| Improvement of ocular symptoms | 28.0 | 25.0 | 31.0 |
| Side effects | 11.0 | 10.0 | 12.0 |
| Epistaxis | 100.0 | 0.0 | 0.0 |
| Treatment with budesonide aquous nasal spray | |||
| Improvement of symptoms | 88.0 | 79.2 | 96.8 |
| Improvement of nasal symptoms | 25.0 | 23.0 | 28.0 |
| Improvement of ocular symptoms | 37.0 | 33.0 | 41.0 |
| Side effects | 44.0 | 40.0 | 48.0 |
| Epistaxis | 44.0 | 40.0 | 48.0 |
Probability calculations based on three efficacy and three safety parameters summarized in a therapeutic index [10]