Table 2.
Gene ontology analysis of the differentially expressed genes for FTC, PTC and ATC
| Subtype (Exp) | GO-ID | p-value | corr p-value | x | n | X | Description |
|---|---|---|---|---|---|---|---|
| FTC ⇑ | 9987 | 4.8469E-9 | 1.2888E-5 | 185 | 9365 | 264 | cellular process |
| 44459 | 2.6863E-8 | 2.9147E-5 | 61 | 1998 | 264 | plasma membrane part | |
| 786 | 3.2885E-8 | 2.9147E-5 | 10 | 64 | 264 | nucleosome | |
| 32502 | 2.4620E-7 | 1.6366E-4 | 82 | 3235 | 264 | developmental process | |
| 6334 | 3.6737E-7 | 1.9537E-4 | 10 | 82 | 264 | nucleosome assembly | |
| 31497 | 5.7722E-7 | 2.5580E-4 | 10 | 86 | 264 | chromatin assembly | |
| 7155 | 8.6760E-7 | 2.6280E-4 | 29 | 711 | 264 | cell adhesion | |
| 22610 | 8.9259E-7 | 2.6280E-4 | 29 | 712 | 264 | biological adhesion | |
| 65004 | 9.8169E-7 | 2.6280E-4 | 10 | 91 | 264 | protein-DNA complex | |
| assembly | |||||||
| 30054 | 9.9358E-7 | 2.6280E-4 | 24 | 521 | 264 | cell junction | |
| PTC ⇑ | 5576 | 8.4568E-20 | 3.4089E-16 | 124 | 2025 | 471 | extracellular region |
| 32502 | 2.2428E-18 | 4.5203E-15 | 164 | 3231 | 471 | developmental process | |
| 44421 | 7.1367E-18 | 9.5893E-15 | 77 | 985 | 471 | extracellular region part | |
| 48731 | 1.0396E-17 | 1.0476E-14 | 134 | 2420 | 471 | system development | |
| 48856 | 1.4340E-17 | 1.1561E-14 | 142 | 2653 | 471 | anatomical structure | |
| development | |||||||
| 7275 | 1.2464E-15 | 8.3739E-13 | 148 | 2969 | 471 | multicellular organismal | |
| development | |||||||
| 9611 | 3.1138E-15 | 1.7931E-12 | 51 | 541 | 471 | response to wounding | |
| 31012 | 6.5039E-14 | 3.2771E-11 | 38 | 340 | 471 | extracellular matrix | |
| 48513 | 1.1744E-13 | 5.2599E-11 | 101 | 1790 | 471 | organ development | |
| 48518 | 1.4424E-13 | 5.8143E-11 | 116 | 2207 | 471 | positive regulation of | |
| biological process | |||||||
| ATC ⇑ | 22403 | 2.6565E-31 | 1.6569E-27 | 105 | 436 | 1205 | cell cycle phase |
| 7049 | 5.2100E-30 | 1.6247E-26 | 147 | 794 | 1205 | cell cycle | |
| 279 | 1.0473E-29 | 2.1774E-26 | 91 | 352 | 1205 | M phase | |
| 22402 | 1.9707E-29 | 3.0727E-26 | 121 | 583 | 1205 | cell cycle process | |
| 278 | 2.8071E-28 | 3.4578E-25 | 93 | 381 | 1205 | mitotic cell cycle | |
| 280 | 3.8808E-28 | 3.4578E-25 | 71 | 233 | 1205 | nuclear division | |
| 7067 | 3.8808E-28 | 3.4578E-25 | 71 | 233 | 1205 | mitosis | |
| 87 | 4.7977E-28 | 3.7404E-25 | 72 | 240 | 1205 | M phase of mitotic cell cycle | |
| 6950 | 5.0373E-27 | 3.2463E-24 | 240 | 1773 | 1205 | response to stress | |
| 48285 | 5.2048E-27 | 3.2463E-24 | 71 | 242 | 1205 | organelle fission | |
| FTC ⇓ | 44421 | 3.9892E-20 | 1.2027E-16 | 59 | 984 | 270 | extracellular region part |
| 5576 | 1.5267E-18 | 2.3015E-15 | 84 | 2024 | 270 | extracellular region | |
| 5615 | 3.5497E-16 | 3.5674E-13 | 46 | 746 | 270 | extracellular space | |
| 9653 | 3.2978E-15 | 2.4857E-12 | 58 | 1216 | 270 | anatomical structure morphogenesis | |
| 48856 | 2.0741E-14 | 1.2507E-11 | 90 | 2654 | 270 | anatomical structure development | |
| 32502 | 3.6213E-13 | 1.8197E-10 | 99 | 3232 | 270 | developmental process | |
| 48731 | 1.5184E-12 | 6.5398E-10 | 81 | 2420 | 270 | system development | |
| 7275 | 2.0597E-12 | 7.7626E-10 | 92 | 2969 | 270 | multicellular organismal development | |
| 31012 | 1.4050E-11 | 4.7067E-9 | 26 | 340 | 270 | extracellular matrix | |
| 48513 | 4.7085E-11 | 1.4196E-8 | 64 | 1790 | 270 | organ development | |
| PTC ⇓ | 44421 | 7.8517E-13 | 2.8376E-9 | 61 | 985 | 404 | extracellular region part |
| 5615 | 8.2894E-10 | 1.0196E-6 | 46 | 747 | 404 | extracellular space | |
| 48856 | 8.4640E-10 | 1.0196E-6 | 107 | 2655 | 404 | anatomical structure development | |
| 48731 | 2.1381E-9 | 1.9317E-6 | 99 | 2421 | 404 | system development | |
| 5576 | 2.7064E-9 | 1.9562E-6 | 87 | 2026 | 404 | extracellular region | |
| 9653 | 4.1464E-9 | 2.4975E-6 | 61 | 1217 | 404 | anatomical structure morphogenesis | |
| 48513 | 2.6665E-8 | 1.3767E-5 | 77 | 1791 | 404 | organ development | |
| 7275 | 5.2835E-8 | 2.3868E-5 | 110 | 2970 | 404 | multicellular organismal development | |
| 32502 | 5.9933E-8 | 2.4067E-5 | 117 | 3233 | 404 | developmental process | |
| 31012 | 7.5072E-8 | 2.7131E-5 | 26 | 340 | 404 | extracellular matrix | |
| ATC ⇓ | 5737 | 1.2083E-12 | 7.0080E-9 | 837 | 7628 | 1632 | cytoplasm |
| 5622 | 1.4044E-9 | 4.0728E-6 | 1147 | 11273 | 1632 | intracellular | |
| 43296 | 4.8770E-9 | 9.4289E-6 | 27 | 85 | 1632 | apical junction complex | |
| 44444 | 8.0946E-9 | 1.1737E-5 | 574 | 5140 | 1632 | cytoplasmic part | |
| 16327 | 1.1319E-8 | 1.3130E-5 | 27 | 88 | 1632 | apicolateral plasma membrane | |
| 70160 | 2.1881E-8 | 1.7096E-5 | 24 | 74 | 1632 | occluding junction | |
| 5923 | 2.1881E-8 | 1.7096E-5 | 24 | 74 | 1632 | tight junction | |
| 44424 | 2.3581E-8 | 1.7096E-5 | 1107 | 10919 | 1632 | intracellular part | |
| 55114 | 5.1010E-7 | 3.2873E-4 | 98 | 647 | 1632 | oxidation reduction | |
| 5911 | 6.8676E-7 | 3.9832E-4 | 40 | 192 | 1632 | cell-cell junction |
It is shown a set of the top ten categories for each case, overexpressed (⇑) and underexpressed (⇓).
It is shown the GO-ID, the p-value, adj. p-value, number of genes present in the set and the total of number of genes involved in that GO categorie. Finally, the name of the GO is also shown.