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. 2015 Mar 24;14:122. doi: 10.1186/s12936-015-0651-1

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© Park et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Metabolome-wide association study (MWAS). This is the snapshot of metabolites between supernatants from Plasmodium, non-infected and infected cultures at all time points using Manhattan plot on 3270 features. The features from duplicate run were averaged, log2 transformed, and quantile normalized to find out the significant features using false discovery rate (FDR). The dotted line represents FDR q=0.05. The metabolites over this line were the significant metabolites (n=1025) between two groups.