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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Trends Mol Med. 2014 Dec 10;21(2):68–76. doi: 10.1016/j.molmed.2014.12.001

Figure 3. Transmitochondrial monkeys produced by spindle transfer.

Figure 3

A) Spindle transfer (ST) rhesus monkeys, Mito and Tracker, shortly after birth and at 3 years of age.

B) Growth curves based on weight measurements (kg) showing that spindle transfer (ST) offspring were in the normal range for the first 30 months (Mo) of their lives.

C) MtDNA carryover levels (% heteroplasmy) in four monkeys (Mito, Tracker, Spindler and Spindy), as measured in cord blood at birth or in blood and skin at 19 months. The levels were essentially at the limit of detection and did not change significantly over time. From [22], with permission.