Figure 2.
A 16-year-old boy (case 2) with autosomal-dominant RHO, D190N retinitis pigmentosa. (A) Autofluorescence (AF) image of the right macula showing a hypoautofluorescent, inferiorly concave arc around the fovea. Yellow arrowheads correspond to inner segment ellipsoid band disruption detected by spectral-domain OCT (D). (B) Microperimetry mapping shows similar declines in visual sensitivity (dB) across the hyperautofluorescent arc border; however, the losses in sensitivity within the arc are mild in contrast to case 1. (C) Photoreceptor outer segment and retinal pigment epithelial thickness across the fovea compared to retinal thickness in the same area within the ring and abrupt thinning beyond the borders of the ring. (E) Adaptive optics-scanning laser ophthalmoscope images taken at positions 0.5, 1.0, and 1.5 mm (temporally and nasally) from the fovea with position correspondence observed in the dotted boxes in an AF image (A).