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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Arch Toxicol. 2014 Jun 25;89(7):1057–1070. doi: 10.1007/s00204-014-1302-y

Fig. 4.

Fig. 4

TMP and NAC suppressed arsenic-induced intracellular ROS production in HK-2 cells determined by dihydroethidium (DHE) staining and FACS analysis. a, b Induction of intracellular ROS generation in a dose-dependent manner. TMP (100 µM) and NAC (10 mM) inhibited arsenic-induced ROS generation at 3 (c, d) and 24 h (e, f). g Intracellular GSH levels were measured after 24-h sodium arsenite exposure. Values are mean ± SD (n = 3), *p < 0.05 versus Con, **p < 0.01 versus Con