TMP and NAC suppressed arsenic-induced intracellular ROS production in HK-2 cells determined by dihydroethidium (DHE) staining and FACS analysis. a, b Induction of intracellular ROS generation in a dose-dependent manner. TMP (100 µM) and NAC (10 mM) inhibited arsenic-induced ROS generation at 3 (c, d) and 24 h (e, f). g Intracellular GSH levels were measured after 24-h sodium arsenite exposure. Values are mean ± SD (n = 3), *p < 0.05 versus Con, **p < 0.01 versus Con