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. Author manuscript; available in PMC: 2016 Jan 23.
Published in final edited form as: Oncogene. 2014 Sep 29;34(30):3935–3945. doi: 10.1038/onc.2014.324

Figure 1. AIB1 is overexpressed in CRC cell lines and promotes CRC cell proliferation.

Figure 1

(a) Western blot analysis of expression of AIB1 protein in normal colon epithelium cells and 6 CRC cell lines. (b,c,d) Proliferation of CRC cell lines RKO, HCT116, and CT26 transiently transfected with AIB1 siRNA or control siRNA was measured by MTT assay. (e,f,g) Proliferation of CRC cell lines RKO, HCT116, and CT26 stably transfected with AIB1 shRNA or control shRNA was measured by MTT assay. The knockdown efficiency of AIB1 was measured by Western blot analysis. All experiments were performed at least twice with similar results. All data are the means +s.d. (n=3) at each time point. Statistically significant difference: *P<0.05 and **P<0.01(t-test).